The Dune series is abandonware, make sure to follow the installation guide to find the correct version.
The main difference other than platform is that TUC versions of these games require either Bibber's or Medstar's fixed Origin launchers if you want to use mods or launch arguments.
If you enjoy Tib Dawn and RA1, these two games have had recent Remasters which are the best way to play those games. The first three games have been released by EA as freeware, and these freeware versions come prepatched with fan patches, and so are preferable to the ones downloaded from Origin. Just make certain you follow these guides for each game to make sure you set them up correctly, or you may run into problems. The Ultimate Collection on Origin contains every C&C game, excluding the recent Remasters (the Remasters are available on Steam and Origin). The following is a copy-paste I've made that covers how best to play the whole C&C series, it's a little more info than you were after but I think some of it'll apply to you